Advances in synthetic lethality for cancer therapy
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「Advances in synthetic lethality for cancer therapy」文章包含有:「Advancesinsyntheticlethalityforcancertherapy」、「Advancesinsyntheticlethalityforcancertherapy」、「Developmentofsyntheticlethalityincancer」、「NewHorizonsofSyntheticLethalityinCancer」、「Thepowerandthepromiseofsyntheticlethalityforclinical...」、「Thebiologicalessenceofsyntheticlethality」、「UnleashingthePowerofSyntheticLethality」
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Advances in synthetic lethality for cancer therapy
https://www.ncbi.nlm.nih.gov
Clinically, the treatment strategy based on synthetic lethality has three major benefits: (1) a synthetic lethality-based treatment strategy could be utilized against the majority of cancer mutations, (2) synthetic lethality allows simple identification o
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Advances in synthetic lethality for cancer therapy
https://jhoonline.biomedcentra
It has been demonstrated that the synthetic lethal approach can be used to treat breast and ovarian cancer cells by inducing senescence with ...
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Development of synthetic lethality in cancer
https://www.nature.com
Based on these clinical trials, the FDA first approved olaparib for the treatment of advanced-stage, BRCA1/2-mutant ovarian cancers in 2014.
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New Horizons of Synthetic Lethality in Cancer
https://pubs.acs.org
This Perspective focuses on the most recent progress in synthetic lethal targets and their inhibitors, within and beyond the DNA damage response ...
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The power and the promise of synthetic lethality for clinical ...
https://www.sciencedirect.com
Research progress of gene target based on synthetic lethality. SL has already demonstrated efficacy as a therapeutic strategy in targeting certain tumor types ...
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The biological essence of synthetic lethality
https://onlinelibrary.wiley.co
Initially studied in yeast and Drosophila models, the concept of SL has significantly advanced targeted cancer therapies. Hartwell and ...
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Unleashing the Power of Synthetic Lethality
https://www.mdpi.com
With advances in technology, the five most common cancer treatments to date include physiotherapy–surgical resection, radiotherapy, chemotherapy, targeted ...